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Transcriptomics

Unlocking gene expression insights

Bulk, single-cell, and long-read RNA sequencing solutions.

From cost-effective bulk profiling to high-resolution single-cell and long-read analysis, we deliver comprehensive transcriptomic solutions. Our proprietary SmartComplete and Smart-3SEQ protocols, combined with industry-leading platforms (10X Genomics, SeekGene, and the new Illumina 3' scRNA), allow us to uncover transcriptional heterogeneity, novel isoforms, and RNA modifications, even in challenging, low-input, or fragmented samples like nasal swabs and FFPE tissues.

Transcriptomics at the iPsomics lab
Core expertise

Multi-platform capability

Robust sample handling

Specialized protocols for difficult inputs, including fragmented RNA, low-biomass samples (nasal swabs), and single-cell suspensions.

Multi-platform flexibility

Choice of SmartComplete (full-length total RNA), Smart-3SEQ (cost-effective 3' profiling), 10X Genomics, SeekGene, and the Illumina PIPseq solution for optimized single-cell resolution.

Long-Read Precision

Oxford Nanopore Technologies for full-length transcript reconstruction, alternative splicing detection, and direct RNA modification profiling.

End-to-end bioinformatics

Custom pipelines for differential expression, isoform quantification, and cell-type deconvolution.

Applications

Research applications

Biomarker discovery

Identifying transcriptional signatures in blood, tissue, or liquid biopsies for diagnostic development.

Tumor microenvironment (TME)

Deconvoluting complex cell populations and immune infiltration in cancer samples.

Splicing and modification analysis

Detecting alternative splicing events and RNA modifications using long-read sequencing.

Clinical applications

Profiling degraded or low-quality RNA samples (e.g., nasal swabs, archived tissues) where standard kits fail.

Workflow

Sample to insight

Our transcriptomics workflow supports flexible entry points — bring tissue or bring RNA.

1
Flexible Entry
Send Tissue or send RNA — full extraction service OR bring your own RNA to save costs.
2
Quality Control
TapeStation 4200 (RIN/RQN)
3
Library Prep
SmartComplete, Smart-3SEQ, 10X, Nanopore
4
Sequencing
Illumina & Oxford Nanopore
5
Bioinformatics
Isoforms, Deconvolution, Modifications

Not sure your sample qualifies? Contact us to check →

Transcriptomics — common questions

Can you work with degraded RNA?

Yes. Our Smart-3SEQ protocol is specifically designed for fragmented or degraded samples, including FFPE tissue and nasal swabs.

What sequencing platforms do you use?

We run Illumina (NovaSeq, NextSeq) for short-read and Oxford Nanopore for long-read sequencing. Platform choice depends on your research question.

Get in touch

Ready to build your Transcriptomics model?

Tell us about your project and we'll scope a solution for your lab.